This is the standard surgery to treat osmidrosis. A 3–4-cm incision is made at the armpit crease, and the skin and subcutaneous tissues are dissected at the area distributed with armpit hair. Then, aggregated particles of the apocrine glands, fats, and partial hair follicles are completely removed from the back of the skin (en bloc excision). The advantages are as follows: able to confirm no residue of the apocrine gland, the highest clearance rate of bad odor at approximately 95%, and the extremely low recurrence rate. Thus, it is applicable for patients with severe osmidrosis or those who heavily sweat due to exercises and work. The disadvantage is the relatively slow recovery of the surgical wound that leads to poor healing, skin flap necrosis, or subcutaneous hematoma and leaves visible scars in the future.