This technique is frequently performed in young females who are unmarried or without natural birth via vaginal delivery. Because these patients have vaginal muscles and skin with intact elasticity, vaginal mucosal resection or muscular stitching is saved to attain the tightening results, so autologous fat injection is employed to augment the inner wall of the vagina or the periphery of the vaginal opening to enhance the intimacy with male sexual organs during sexual intercourse. In this surgery, adipocytes should first be extracted from other body parts through liposuction and then be radially injected at multiple points and facets and annularly distributed in the vaginal wall. The injection scope extends 5 cm inside the vaginal opening, and the injection depth reaches the superficial tissues between the vaginal mucosa and muscular layer. If a patient has G-spot orgasm disorders, partial fats are also injected to the area near the G-spot to enhance stimulus to the G-spot.

Despite being an economic vaginal augmentation method, fat injection is replaced by the injection of high molecular weight hyaluronic acid (Macrolene or Sub-Q), if the patient does not have excess fats. This method utilizes large-dose hyaluronic acid, whose results last for approximately 6 months and whose costs and benefits greatly differ from those of fat injection.